222 Third — Lease in Cambridge, MA

  • Price: Contact for price
  • Listing type: For lease
  • Asset type: Office
  • Location: Cambridge, MA 02142
  • Submarket: Back Bay

Photos

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Description

Situated in the heart of East Cambridge, the American Twine Building is a historic brick and beam office building located just a short walk from the Kendall Square Red Line and Lechmere Green Line MBTA stations and surround by new restaurants and retail offerings. The building contains suites of assorted sizes and layouts, all with exposed brick and beams and large windows which allow an abundance of natural light throughout. Amenities include on-site reserved parking, 24-hour security, a grab-and-go cafe, showers, and a shared conference room.

Market Context

This office in Cambridge, MA is listed for lease. Compare it against other office listings for lease in Cambridge, MA — view the full market.

As of Q2 2026, the Boston office market showed average asking rents near $46.99/SF/yr, and rents up 2.7% year over year. Source: multiple brokerage reports, Q2 2026.

Rising rents point to a competitive market where well-priced, well-located space leases quickly.

Estimated Market Rate

$2.75/SF/mo – $3.72/SF/mo

Mid: $3.24/SF/mo

Based on comparable properties in similar markets rather than local sales.

By our match to nearby addresses in brokers' reports, this property is in the Back Bay submarket, where average asking rent was $66.86/SF/yr in Cushman & Wakefield's Q2 2026 report.

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